Breast, benign proliferative change [LMP84099]

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Image Details
Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and Death
Diagnosis: 
Fibrocystic and benign proliferative change
Species: 
Human
Organ System: 
Breast
Gender: 
Female
Age: 
63 years
Diagnosis Code: 
ICD-10: N60.3
Slide Contributor Information
Martin
Chang

Keywords

hyperplasia

Clinical History

A section of breast tissue from an excisional biopsy for a mass.

Clinical Discussion

There are a wide range of benign alterations in breast tissue that are not considered “normal histology”, but at the same time are not of clinical significance. One must recognize the full range of these to avoid the temptation to call these changes “atypical” or worse, malignant. This section, taken from a breast cancer case, illustrates some of these changes, including dense stromal fibrosis, benign apocrine cysts with calcifications, usual ductal hyperplasia, radial sclerosing lesion, and pseudoangiomatous stromal hyperplasia.