Breast, Gynecomastia [LMP11035]

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Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and Death
Diagnosis: 
Gynecomastia
Species: 
Human
Organ System: 
Breast
Gender: 
Male
Age: 
33 years
Diagnosis Code: 
ICD-10: N62
Slide Contributor Information
Elzbieta
Slodkowska

Keywords

Gynecomastia

Clinical History

Bilateral breast enlargement

Clinical Discussion

Most common during puberty and 6-7 decade, due to hormonal imbalance (increased estrogen and/or decreased androgen). In the early (florid) stage there is epithelial hyperplasia with tufting and hypercellular often PASH-like stroma with loose myxoid periductal stroma. In the late (fibrous) stage there is stromal fibrosis and atrophy of epithelium.