Duodenum, tubular adenoma [LMP81137]
Keywords
tubular adenoma, FAP, duodenum, polyposis
Clinical History
Patient underwent a subtotal colectomy with ileo-rectal anastomosis. He is known to have 25-50 small polyps in the remaining rectum. During routine upper endoscopy, the following polyps were seen in the duodenum.
Clinical Discussion
After the colorectum, the duodenum is the second most commonly affected site to polyp development in Familial Adenomatous Polyposis (FAP). Duodenal/periampullary adenocarcinoma is the leading cause of death in FAP after colorectal cancer. While greater than 95% of FAP patients develop adenomatous polyps in the duodenum during their lifetime, only 5% go on to develop cancer. Routine screening with upper gatrointestinal endoscopy is now commonplace in an attempt to decrease the cancer rate. This image, and its supplementary image, show 2 duodenal adenomas from the same patient.
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