Skin, Irritated seborrheic keratosis [LMP61653]

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Image Details
Diagnostic Modality: 
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Disease Category: 
Neoplasia
Diagnosis: 
Irritated seborrheic keratosis
Species: 
Human
Organ System: 
Skin
Gender: 
Male
Age: 
62 years
Diagnosis Code: 
ICD-10: L82
Slide Contributor Information
Boles, D., Sade, S.

Clinical History

62 year-old mail with yellow-tan plaque on his right lower leg.

Clinical Discussion

Irritated seborrheic keratosis is a benign keratinocytic proliferation, generally occurring in older adults. Sections show acanthosis, hyperkeratosis with pronounced reactive appearance including squamous whorls and scattered mitotic figures. There is generally surface crusting. The appearance may be mistaken for well differentiated squamous cell carcinoma.