Skin, Polymorphic light eruption [LMP58920]

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Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and Death
Diagnosis: 
Polymorphic light eruption
Species: 
Human
Organ System: 
Skin
Gender: 
Male
Age: 
40 years
Diagnosis Code: 
ICD-10: L56.4
Slide Contributor Information
Morgan, S., Mete, O.

Keywords

polymorphic, polymorphous, light

Clinical History

Acute monomorphic papular eruption in the chest right after a day at the beach in July.

Clinical Discussion

Polymorphic light eruption is the most common photodermatosis. It presents in young adults as papular rash, vesicles or plaques 18-24 hours after light exposure usually in the spring/summer. Microscopically, it shows perivascular lymphohistiocytic infiltrate in superficial dermis. Papillary dermal edema, epidermal acanthosis, and spongiosis are also seen. There is variable increase in eosinophils and neutrophils.