Testis, large cell calcifying Sertoli cell tumour [LMP14469] | LMP - Digital Laboratory Medicine Library

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Testis, large cell calcifying Sertoli cell tumour [LMP14469]

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Diagnostic Modality:

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Disease Category:

Diagnosis:

Large cell calcifying Sertoli cell tumour

Species:

Organ System:

Lower Urinary Tract and Male Genital System

Gender:

Male

Age:

12 years

Diagnosis Code:

ICD-10: D40.1 | ICD-O: 8642/1

Slide Contributor Information

Kolin, D., Ngan, B.

Keywords

Sertoli cell, sex-cord stromal, testicular, testis

Clinical History

12-year-old male with multiple, bilateral, testicular masses.

Clinical Discussion

Large cell calcifying Sertoli cell tumours are unusual sex-cord stromal neoplasms of the testis, of uncertain malignant potential. Histologically, they are composed of solid tubules or nests of cells with abundant eosinophilic cytoplasm and prominent nucleoli. As the name suggests, calcifications are common. The young patient age and multifocality suggest an underlying genetic syndrome. Large cell calcifying Sertoli cell tumours are associated with both Carney complex and Peutz-Jeghers syndrome.

Related Content

Wholeslide Image ID:

LMP76596 Thumbnail

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Testis, large cell calcifying Sertoli cell tumour [LMP76596]

Organ System:

Lower Urinary Tract and Male Genital System

Gender:

Male

Species:

Human

Diagnostic Modality:

Whole Slide Image

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