Endometrium, atypical hyperplasia with progestin effect [LMP90326]
Keywords
EIN, endometrial intraepithelial neoplasia, complex atypical hyperplasia
Clinical History
Infertility and endometrial “polyps”. An endometrial biopsy was performed.
Clinical Discussion
Atypical hyperplasia of the endometrium (also “endometrial intraepithelial neoplasia”) is a precursor for endometrial cancer. Risk factors include obesity and unopposed estrogens. It is characterized by a crowded proliferation of clonal-appearing glands. Squamous morules can also be seen.
A link to a slide of a biopsy taken before treatment with high‐dose progestins is provided in the Related Content section. Images of the ovary and endometrium at the time of hysterectomy are also provided in the Related Content section. These slides highlight the appearance of atypical hyperplasia superimposed on progestin‐treatment changes.
A link to a slide of a biopsy taken before treatment with high‐dose progestins is provided in the Related Content section. Images of the ovary and endometrium at the time of hysterectomy are also provided in the Related Content section. These slides highlight the appearance of atypical hyperplasia superimposed on progestin‐treatment changes.
Related Content
LT OVARY
HYSTERECTOMY
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