Gastroesophageal junction, Helicobacter heilmannii gastritis, Helicobacter stain [LMP55820]
Keywords
Helicobacter, chronic, active, gastritis, heilmannii
Clinical History
Inflammation of the esophagus.
Clinical Discussion
The gastric cardia can extend into the lower esophagus, and become inflamed causing symptoms of esophagitis. Sections show gastric-type mucosa with preserved glandular architecture. There is a mild increase in lymphoplasmacytic infiltrate in the superficial lamina propria which is more prominent in antral biopsy (part C). There is minimal focal active inflammation with single neutrophils infiltrating the pits in the body biopsy (part D). There are scattered "corkscrew" shaped coiled spirals of Helicobacter heilmannii organisms present on the luminal surface as well as coccoid forms infiltrating the crypt epithelium, seen both on H&E (see Related Content) and immunostains (this slide). There are no granulomas or giant cells.
Related Content
Helicobacter heilmannii with a corkscrew appearance present at the luminal surface of a gastric antral crypt.
Immunohistochemical stain highlighting Helicobacter heilmannii at the luminal surface of a gastric antral crypt.
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