Head, Acinic cell carcinoma [LMP71461]

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Image Details
Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Neoplasia
Diagnosis: 
Acinic cell carcinoma
Species: 
Human
Organ System: 
Head and Neck
Gender: 
Male
Age: 
45 years
Slide Contributor Information
Duan, K., Lu, F.

Keywords

zymogen granules, malignant salivary gland tumor

Clinical History

Parotid mass.

Clinical Discussion

Acinic cell carcinoma (ACC) is a malignant salivary gland tumor that commonly affects the parotid gland. Complete surgical resection is usually the treatment of choice. ACC is generally associated with good prognosis although recurrence may occur. A characteristic feature of acinic cell carcinoma pertains to the presence of zymogen granules, which are dense blue to purple, fine to coarse, granules that are generally PAS(+) and diastase-resistant.