Large intestine, Dedifferentiated gastrointestinal stromal tumour (GIST), IDOG1 [LMP59371]

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Diagnostic Modality: 
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Disease Category: 
Neoplasia
Diagnosis: 
Dedifferentiated gastrointestinal stromal tumour (GIST)
Species: 
Human
Organ System: 
Bones, Joints, and Soft-Tissue Tumours
Gender: 
Female
Age: 
62 years
Slide Contributor Information
Armstrong, S., Dickson, B.

Keywords

soft tissue, colon, large intestine, large bowel, neoplasm

Clinical History

Large bowel lesion.

Clinical Discussion

Key histologic features: As with other GISTs, but pleomorphism; brisk mitoses.

Molecular: +PDGFRA.

NB: Chronic imatinib (see related content for reference).

Related Content

Related External Links: 
Dedifferentiation in gastrointestinal stromal tumor to an anaplastic KIT-negative phenotype: a diagnostic pitfall: morphologic a
Wholeslide Image ID: 
LMP96328 Thumbnail
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Large intestine, Dedifferentiated gastrointestinal stromal tumour (GIST), IC117 [LMP96328]

Organ System: 
Bones, Joints, and Soft-Tissue Tumours
Gender: 
Female
Species: 
Human
Diagnostic Modality: 
Whole Slide Image
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