Lung, Malignant mesothelioma [LMP98594]

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Diagnostic Modality: 
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Disease Category: 
Neoplasia
Diagnosis: 
Malignant mesothelioma
Species: 
Human
Organ System: 
Lung
Gender: 
Male
Age: 
62 years
Diagnosis Code: 
ICD-10: C45.7 | ICD-O: 9050/3
Slide Contributor Information
Mullen, B., Nanji, S., Chang, M.

Keywords

pleural, asbestos

Clinical History

62-year-old male construction worker with increasing shortness of breath and pleural based densities on a routine chest x-ray film.

Clinical Discussion

Most diffuse malignant mesothelioma arise in workers with direct occupational exposure to asbestos. The incidence of malignant mesothelioma is increasing because of prolonged latency period (> 30 years) from asbestos use and exposure. Initial chest x-ray films of patients with malignant mesothelioma reveal pleural effusions in over 75%. Mesotheliomas have a varied histologic appearance and include epithelial, sarcomatoid and biphasic patterns.