Ovary, endometrioid carcinoma [LMP62167]

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Diagnostic Modality: 
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Disease Category: 
Neoplasia
Diagnosis: 
Ovarian endometrioid carcinoma
Species: 
Human
Organ System: 
Female Genital Tract
Gender: 
Female
Age: 
36 years
Diagnosis Code: 
ICD-10: C56 | ICD-O: 8380/3
Slide Contributor Information
Chang, M.

Keywords

Ovary, endometrioid, adenocarcinoma

Clinical History

Right ovarian mass resected at the time of cesarian section.

Clinical Discussion

Endometrioid carcinoma is the second most common ovarian epithelial malignancy. It is characterized by epithelium resembling uterine endometrium. Association with endometriosis is common, and risk factors are thought to be shared with endometrial endometrioid carcinoma including unopposed estrogens and Lynch syndrome. In this case, the diagnostic features are confluent glandular proliferation with cribriform and villoglandular growth along with stromal invasion. The epithelial cells show columnar and polarized morphology. Focal mucinous or squamous differentiation does not alter the classification.