Ovary, metastatic melanoma [LMP80762]

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Image Details
Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Neoplasia
Diagnosis: 
Metastatic malignant melanoma
Species: 
Human
Organ System: 
Female Genital Tract
Gender: 
Female
Age: 
Unknown
Diagnosis Code: 
ICD-10: C79.6
Slide Contributor Information
Shabin
Nanji

Keywords

ovary, metastasis, melanoma

Clinical History

Taken from an Ovarian Mass

Clinical Discussion

In this case, we are presented with a poorly differentiated epithelioid neoplasm involving the ovary and forming a large expansile mass. The cells have abundant mitotic activity and large round nuclei, with some prominent nucleoli. In some areas, melanin pigment can be appreciated; however, much of the tumour is amelanotic. The differential diagnosis includes primary ovarian cancers, including serous carcinoma, transitional cell carcinoma, and malignant stromal tumours. However, the morphology and presence of melanin pigment should prompt the diagnosis of metastatic melanoma.