Pancreas, Mucinous cystic neoplasm, low grade [LMP25614]

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Image Details
Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Neoplasia
Diagnosis: 
Mucinous cystic neoplasm, low grade
Species: 
Human
Organ System: 
Pancreas
Gender: 
Female
Age: 
35 years
Diagnosis Code: 
ICD-10: C25 | ICD-O: 8470/0
Slide Contributor Information
Shivji, S., Hsieh, E.

Keywords

mucinous cystic neoplasm, cystic lesion, pancreatic, pancreas, borderline, cyst

Clinical History

35 year-old female with an incidental finding of a 2 cm cystic lesion in the body of the pancreas on imaging. It does not connect with either the main duct or side branch ducts.

Clinical Discussion

Mucinous cystic neoplasm is an important entity in the differential diagnosis of cystic lesions of the pancreas. Like intraductal papillary mucinous neoplasm (IPMN), it is a mucin-producing epithelial lesion which can harbor low grade, moderate, or severe dysplasia. It is distinguished from IPMN by the presence of ovarian type stroma and a lack of continuity with the main or side branch ducts of the pancreas. Mucinous cystic neoplasm represents approximately 2% of all exocrine pancreatic neoplasms, and shows a 9:1 female to male predominance, with an average age of 50 years at diagnosis. This case is an example of a mucinous cystic neoplasm with low grade dysplasia demonstrating the classic ovarian type stroma.