Soft Tissue, Adenomatoid tumour [LMP29370]

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Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Neoplasia
Diagnosis: 
Adenomatoid tumour
Species: 
Human
Organ System: 
Bones, Joints, and Soft-Tissue Tumours
Gender: 
Female
Age: 
51 years
Diagnosis Code: 
ICD-10: D26 | ICD-O: 9054/0
Slide Contributor Information
Hodgson, A., Lu, F.

Keywords

adenomatoid tumour, pelvic tumour, mesothelial

Clinical History

Pelvic mass (intrapelvic soft tissue mass).

Clinical Discussion

Adenomatoid tumour is a benign neoplasm of mesothelial origin. It is typically composed of tubules, microcystic spaces, and vascular-type slits and is lined by bland cuboidal to flattened mesothelial cells. Stromal lymphocytes may also be present. Although this lesion is more commonly found in the uterus, it is the most frequently encountered benign neoplasm of the fallopian tube. Typically, this lesion is seen in a subserosal location though can be located elsewhere.

Grossly, this lesion tends to be small, well circumscribed but unencapsulated, and yellow-gray in colour. The differential diagnoses are adenocarcinoma (particularly at frozen section), lymphangioma, and leiomyoma. Useful immunohistochemical stains which are positive in this tumour are LMWK, WT1, and calretinin.