Uterus, Adenomatoid tumour [LMP32070]

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Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Neoplasia
Diagnosis: 
Adenomatoid tumour
Species: 
Human
Organ System: 
Female Genital Tract
Gender: 
Female
Age: 
44 years
Diagnosis Code: 
ICD-10: D26.1 | ICD-O: 9054/0
Slide Contributor Information
Yoon, J., Latta, E.

Keywords

adenomatoid tumour, benign mesothelioma, benign adenomatoid mesothelioma

Clinical History

Hysterectomy specimen.

Clinical Discussion

Adenomatoid tumours are benign tumours that can be seen in the uterine corpus, and it is thought to be of mesothelial origin. It is thus also known as benign mesothelioma or benign adenomatoid mesothelioma. Like many visceral organs, Müllerian organs are also partially covered by a mesothelial lining. In the gynaecological tract, adenomatoid tumours are seen most commonly in the uterine corpus (particularly the fundus), but it can also be seen in the fallopian tubes and the ovarian hilum.

Malignant mesothelioma of the uterus is an extremely rare entity.

Histologically, the tumour consists of cysts and open tubules, seen intimately admixed with a more solid growth. Immunostaining for mesothelial markers, such as calretinin, D2-40, or WT-1 can be used to confirm the diagnosis, but histology is generally sufficient for the diagnosis.