Skin, Pilomatrixoma [LMP39099]

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Diagnostic Modality: 
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Disease Category: 
Neoplasia
Diagnosis: 
Pilomatrixoma
Species: 
Human
Organ System: 
Skin
Gender: 
Female
Age: 
40 years
Diagnosis Code: 
ICD-10: D23 | ICD-O: 8110/0
Slide Contributor Information
Boles, D., Sade, S.

Clinical History

40 year-old female with a firm nodule on forehead.

Clinical Discussion

Pilomatrixoma is a benign adnexal tumour of the skin showing matrical differentiation from hair follicles. Sections show a lesion composed of nests of epithelial cells including viable basaloid cells and obsolete "ghost" cells. The nests are separated by fibrous tissue containing calcification and foreign body giant cell reaction.