Skin, Squamous cell carcinoma, basaloid variant [LMP69982]

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Image Details
Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Neoplasia
Diagnosis: 
squamous cell carcinoma, basaloid variant, SCC, BSCC
Species: 
Human
Organ System: 
Skin
Gender: 
Male
Age: 
93 years
Diagnosis Code: 
ICD-10: C44 | ICD-O: 8083/3
Slide Contributor Information
Yoon, J., Ghazarian, D.

Keywords

squamous cell carcinoma, basaloid, SCC, BSCC

Clinical History

93-year old with a forearm lesion.

Clinical Discussion

Squamous cell carcinoma (SCC) is a non-melanocytic lesion derived from keratinocytes in the epidermal layer. It is the second-most common tumour arising from sun-exposed skin, after basal cell carcinoma.

While squamous and basal cell carcinomas can generally be distinguished with relative ease, there is a certain morphological spectrum, with this lesion representing perhaps an intermediate ground between the two entities. The distinction between basal cell carcinoma (BCC) (with squamoid features) is based on the typical features expected of BCC, such as retraction artefact and basal palisading.