Breast, Silicone granuloma [LMP32563]

LMP32563 Thumbnail
View the Zoomify Image
Image Details
Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and Death
Diagnosis: 
Silicone granuloma
Species: 
Human
Organ System: 
Breast
Gender: 
Female
Age: 
43 years
Slide Contributor Information
Chang, M.

Keywords

breast implant, foreign material

Clinical History

Breast implant with associated nodule.

Clinical Discussion

Silicone is commonly used as a filling for breast implants, and is generally inert if implant rupture occurs. In this case, small globules of silicone are present in tissue, and can be seen as empty spaces. Macrophages have attempted, unsuccessfully, to resorb the material, resulting in a granuloma formation. Shown here is the implant capsule.