Heart, Papillary muscle ischemic necrosis [LMP89048]

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Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and Death
Diagnosis: 
Papillary muscle ischemic necrosis
Species: 
Human
Organ System: 
Heart
Gender: 
Female
Age: 
36wk fetus
Diagnosis Code: 
ICD-10: I23.5
Slide Contributor Information
Nanji, S., Chang, M.

Keywords

fetal, cardiac, infarction

Clinical History

36 week (corrected) gestational age infant with a perinatal asphyxial injury who died one week post-partum.

Clinical Discussion

The papillary muscles are end-arterial territories, and as such are susceptible to hypoperfusion in episodic hypotension. In this case, the episode of perinatal asphyxia has led to ischemic pan necrosis of the papillary muscle myocardium.