Placenta, villitis of unknown etiology [LMP59445]

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Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Acute and Chronic Inflammation
Diagnosis: 
Chronic villitis; unknown etiology
Species: 
Human
Organ System: 
Female Genital Tract
Gender: 
Female
Diagnosis Code: 
ICD-10: O43.9
Slide Contributor Information
Keating, S.

Keywords

placenta

Clinical History

Taken from a term placenta

Clinical Discussion

The findings are of a term placenta with excessive chronic inflammatory cells in numerous chorionic villi, diagnostic of chronic villitis. The common causes of villitis include bacteria, toxoplasma, herpes simplex, cytomegalovirus, and syphilis (T. pallidum) - TORCH organisms. In this case, further evaluation for these organisms was negative. The diagnosis for villitis of unknown etiology is a diagnosis of exclusion, but is commonly thought to have an immunologic cause.