Stomach, granulomatous gastritis [LMP43199]

LMP43199 Thumbnail
View the Zoomify Image
Image Details
Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Acute and Chronic Inflammation
Diagnosis: 
Focal chronic active gastritis with granulomatous inflammation, in keeping with known Crohn's disease
Species: 
Human
Organ System: 
Gastrointestinal Tract
Gender: 
Male
Age: 
53 years
Diagnosis Code: 
ICD-10: K29.6
Slide Contributor Information
Forse, C., Chang, M.

Keywords

granulomatous gastritis, Crohn's disease

Clinical History

A man with known Crohn's disease presents with epigastric pain.

Clinical Discussion

Granulomatous gastritis is a descriptive diagnosis used when granulomas are observed in gastric mucosa. The most common causes of granulomatous inflammation in the stomach include sarcoidosis, Crohn's disease, foreign material, infections (i.e. TB, histoplasma capsulatum, syphilis), common variable immunodeficiency and systemic vasculitides (i.e. Wegener's granulomatosis). In addition to granulomas, Crohn's disease in the stomach may also manifest as (1) focally enhanced gastritis characterized by lymphocytes and neutrophils around single crypts with minimal inflammation in the adjacent gastric mucosa and/or (2) antral stenosis.