Lymph Node, Hodgkin lymphoma, nodular sclerosis type [LMP31070]

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Diagnostic Modality: 
Whole Slide Image
Disease Category: 
Neoplasia
Diagnosis: 
Hodgkin lymphoma, nodular sclerosis type
Species: 
Human
Organ System: 
White Blood Cells, Lymph Nodes, Spleen, and Thymus
Gender: 
Female
Age: 
43 years
Diagnosis Code: 
ICD-10: C81.1 | ICD-O: 9663/3
Slide Contributor Information
Yoon, J., Lu, F.

Keywords

NHCSL, Hodgkin’s, B-cell, Classical

Clinical History

Right neck mass.

Clinical Discussion

Hodgkin lymphoma (HL) is a B-cell neoplasm, where the Reed Sternberg (RS) cells are often derived from a B-cell with a "crippled" immunoglobulin gene. WHO classification divides HL into two large categories: classical and nodular lymphocyte-predominant. While the classical type is defined by the RS cells, they are absent in the nodular lymphocyte-predominant type. Among the classical HLs, different subtypes exist, and this case is that of nodular sclerosis type.

Other examples of Hodgkin Lymphoma are: LMP80112, LMP90590, LMP72157 (see Related Content section).

Related Content

Related External Links: 
LMP80112 - Lymph Node, Hodgkin lymphoma
LMP90590 - Lymph Node, Classical Hodgkin lymphoma
LMP72157 - Lymph Node, Nodular lymphocyte predominant Hodgkin lymphoma